Xelestal

Xelestal is composed of proprietary formulation containing 60% (w/w) of microspheric calcium hydroxyapatite (CaHA) distributed in a gel carrier.
 
After injection, the Ca-HA microspheres form a network at the injection site by stimulating collagen and elastin neosynthesis in surrounding fibroblasts through the action of calcium ions. This process results in a youthful and dynamic appearance, with a dense network of collagen and elastin fibers complementing the filler effect. Eventually, the Ca-HA is fully absorbed and replaced by a newly formed collagen network that provides sustainable structural support. Biocompatible and fully biodegradable, the Ca-HA microspheres are metabolized through macrophage fragmentation and phagocytosis, transforming into calcium and phosphate ions. Once the degradation and absorption mechanism is complete, the released ions are identical to those naturally present in the body and are metabolically cleared.